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Tuesday, September 25 • 9:00am - 11:00am
The animal germline

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Emilie Demoinet

McGill University
Tuesday September 25, 2012 09:30 - 09:45 @ Rhodes 8    Stress-dependent transgenerational reduction in brood size and offspring fertility involves AMPK in C. elegans Abstract: Environmentally triggered phenotypes that are heritable from one generation to the next have been found to be associated with DNA methylation and chromatin alterations, causing changes in gene expression. For example, epigenetic alterations arising around... Read More →

Saadi Khochbin

Institut Albert Bonniot
Tuesday September 25, 2012 10:30 - 11:00 @ Rhodes 8   Molecular basis of haploid male genome programming Abstract: Post-meiotic male genome compaction could be considered as conceptually related to sporulation in lower eukaryotes or pollen formation in plants, all involving post-meiotic genome compaction mechanisms of completely unclear nature. In mammals, the current knowledge implies a post-meiotic stepwise replacement of histones... Read More →

Ruth Lehmann

Langone Medical Center, Skirball Institute
Tuesday September 25, 2012 09:00 - 09:30 @ Rhodes 8    Protecting the Germline Abstract: Setting germ cells apart from other cells in the body is crucial for maintenance of all sexually reproducing species. In Drosophila, primordial germ cells (PGCs) from under the control of maternally synthesized germ plasm, while somatic cellularization relies on new, zygotic transcription. Like mice and other species, Drosophila PGCs... Read More →

Huaibiao Li

Leibniz Institute for Age Research - Fritz Lipmann Institute
Tuesday September 25, 2012 10:15 - 10:30 @ Rhodes 8    A common regulator of spermatogenesis and oogenesis with centrosomal function Abstract: Spermatogenesis and oogenesis, the processes of development of mature gametes, have common features but are regulated by distinct mechanisms. In mammals, mature sperm develops via post-embryonic proliferation and differentiation of spermatogonial stem cells, while oocytes, which... Read More →

Mitinori Saitou

Kyoto University
Tuesday September 25, 2012 09:45 - 10:15 @ Rhodes 8    Mechanism and reconstitution in vitro of germ cell specification in mice Abstract: The germ cell lineage ensures the creation of new individuals, thereby perpetuating and diversifying the genetic and epigenetic information across the generations.  We have been investigating signaling, global transcription and epigenetic dynamics associated with germ cell specification... Read More →

Tuesday September 25, 2012 9:00am - 11:00am
Rhodes 8

Attendees (7)