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Monday, September 24 • 3:00pm - 5:00pm
Microtubule cytoskeleton

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Mónica Bettencourt-Dias

The Instituto Gulbenkian de Ciência (IGC)
Monday September 24, 2012 15:00 - 15:30 @ Rhodes 7  Tuesday September 25, 2012 12:30 - 14:00 @ Rhodes 6    BLD10/CEP135 is a microtubule-­‐associated protein that controls the formation of the flagellum central microtubule pair Abstract: Cilia and flagella are structures involved in a variety of developmental processes and human diseases, including ciliopathies and sterility. We investigate how the... Read More →

Andrea Musacchio

MPI für molekulare Physiologie
Monday September 24, 2012 16:30 - 17:00 @ Rhodes 7    The persuasive biochemical logic of kinetochores Abstract: The main focus of our laboratory is the reconstitution of kinetochores, and of their dynamic interactions with the spindle assembly checkpoint. Kinetochores are large proteinaceous disks that are built on centromeric DNA. In mitosis, they provide a site of attachment of chromosomes to the mitotic spindle. The spindle... Read More →

François Nédélec

EMBL, Structural and Computational Biology
Monday September 24, 2012 15:45 - 16:15 @ Rhodes 7   Design principles of yeast spindles Abstract: Bundled cytoskeletal arrays are a universal feature of eukaryotic cells. The anaphase B spindle from fission yeast serves as an excellent model system for studying cytoskeletal arrays under compressive forces as it can be perturbed genetically, is easily visualized using electron or light microscopy and has an organization that is... Read More →
avatar for Iva Tolic-Norrelykke

Iva Tolic-Norrelykke

Max Planck Institute of Molecular Cell Biology and Genetics
Monday September 24, 2012 16:15 - 16:30 @ Rhodes 7    Dynein switches from diffusion along the microtubule to directed movement upon binding to the cortex: a single-molecule in vivo study Abstract: Cytoplasmic dynein is a motor protein that walks along microtubules and in doing so positions organelles in the cell. Dynein uses microtubules either as tracks to transport organelles, proteins and RNAs, or as ropes to pull on... Read More →

Catarina Vicente

University of Oxford
Monday September 24, 2012 15:30 - 15:45 @ Rhodes 7   Elucidating the pathway of centrosome formation in Drosophila Abstract: Centrosomes are cellular organelles that comprise two centrioles surrounded by pericentriolar material (PCM). Although a conserved core set of proteins that are required for centriole duplication and PCM recruitment have been identified in Drosophila, little is known about their order of recruitment. This is... Read More →

Monday September 24, 2012 3:00pm - 5:00pm
Rhodes 7

Attendees (8)