The EMBO Meeting

Monday September 24, 2012 15:00 - 15:30 @ Rhodes 7  Tuesday September 25, 2012 12:30 - 14:00 @ Rhodes 6    BLD10/CEP135 is a microtubule-­‐associated protein that controls the formation of the flagellum central microtubule pair Abstract: Cilia and flagella are structures involved in a variety of developmental processes and human diseases, including ciliopathies and sterility. We investigate h... Read More →

Monday September 24, 2012 16:30 - 17:00 @ Rhodes 7    The persuasive biochemical logic of kinetochores Abstract: The main focus of our laboratory is the reconstitution of kinetochores, and of their dynamic interactions with the spindle assembly checkpoint. Kinetochores are large proteinaceous disks that are built on centrom... Read More →

Monday September 24, 2012 15:45 - 16:15 @ Rhodes 7   Design principles of yeast spindles Abstract: Bundled cytoskeletal arrays are a universal feature of eukaryotic cells. The anaphase B spindle from fission yeast serves as an excellent model system for studying cytoskeletal arrays under compressive forces as it can be perturbed... Read More →

Monday September 24, 2012 16:15 - 16:30 @ Rhodes 7    Dynein switches from diffusion along the microtubule to directed movement upon binding to the cortex: a single-molecule in vivo study Abstract: Cytoplasmic dynein is a motor protein that walks along microtubules and in doing so positions organelles in the cell. Dynein uses microtubules eithe... Read More →

Monday September 24, 2012 15:30 - 15:45 @ Rhodes 7   Elucidating the pathway of centrosome formation in Drosophila Abstract: Centrosomes are cellular organelles that comprise two centrioles surrounded by pericentriolar material (PCM). Although a conserved core set of proteins that are required for centriole duplication and P... Read More →