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Sunday, September 23 • 11:00am - 1:00pm
Membrane trafficking

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Speakers
JB

John Briggs

EMBL, Structural and Computational Biology
Sunday September 23, 2012 12:30 - 13:00 @ Rhodes 8    The structure and assembly of coated vesicles Abstract: Transport between compartments of eukaryotic cells is mediated by coated vesicles. The archetypal protein coats COPI, COPII and clathrin are conserved from yeast to human. We are applying cryo-electron tomography and correlative light and electron microscopy to study the structure and assembly of coated... Read More →
MG

Malgorzata Garstka

Netherlands Cancer Institute
Sunday September 23, 2012 11:30 - 11:45 @ Rhodes 8    Tollip controls transport of MHC class II molecules Abstract: Major histocompatibility complex (MHC) class II molecules present exogenous antigens to CD4+ T cells that modulate immune responses. MHC class II compartment (MIIC) constitutes a key hub for MHC II antigen presentation, wherein the endocytic, exocytic and degradation pathways intersect. Malfunctions along... Read More →
HR

Howard Riezman

University of Geneva - Sciences II
Sunday September 23, 2012 11:45 - 12:15 @ Rhodes 8    Systematic lipidomic analysis of yeast mutants reveals novel regulation of lipid homeostasis and plasma membrane/ER communication Abstract: We have performed an unbiased, systematic, lipidomics analysis of two collections of yeast mutants ; in the early secretory pathway previously used for an epistatic miniarray profiling (Schuldiner et al, 2005) and a collection of yeast... Read More →
MS

Margaret S. Robinson

University of Cambridge - CIMR
Sunday September 23, 2012 11:00 - 11:30 @ Rhodes 8    Clathrin-mediated trafficking analysed by proteomics and genomics Abstract: Clathrin-coated vesicles (CCVs) transport cargo proteins from one membrane compartment of the cell to another. We have used two approaches to investigate clathrin-mediated trafficking: proteomics and genomics. For the proteomics studies, we made use of our “knocksideways” system to... Read More →
AW

Ann Wehman

Skirball Institute, NYU School of Medicine
Sunday September 23, 2012 12:15 - 12:30 @ Rhodes 8    The lipid flippase TAT-5 inhibits the budding of extracellular vesicles from the surface of C. elegans embryos Abstract: Cells release extracellular vesicles (ECVs) that can influence differentiation, modulate the immune response, promote coagulation, and induce metastasis. Many ECVs form by budding outwards from the plasma membrane, but the molecules that regulate budding... Read More →


Sunday September 23, 2012 11:00am - 1:00pm
Rhodes 8

Attendees (11)